Merck Anti-Myosin Va (LE-16) antibody produced in rabbit

Anti-Myosin Va (LE-16) antibody produced in rabbit

~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen 190 kDa

species reactivity

rat, chicken

향상된 검증

independent
Learn more about Antibody Enhanced Validation

농도

~0.5 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using rat and chicken cerebellum sections
microarray: suitable
western blot: 1:500 using a rat brain extract

UniProt 수납 번호

Q02440

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... MYO5A(4644)
mouse ... Myo5a(17918)
rat ... Myo5a(25017)

Myosin Va (p190) is a member of the unconventional class of myosins, distinct from both the myosins I and myosin II. It is present in neuronal and non neuronal cells of the brain. Class V myosins are widely expressed actin-based motors. Class V myosins have two motor head domains typical of myosins, and an extended regulatory neck domain with six tandem IQ domains that bind multiple calmodulin light chains. In addition, myosin V contains a unique 400 amino acids globular tail domain that may direct myosin V to its target or determine the cargo to which it binds.