Merck Anti-LRRK2 (C-terminal region) antibody produced in rabbit

Anti-LRRK2 (C-terminal region) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~240 kDa

species reactivity

human, rat, mouse

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

농도

~1.0 mg/mL

technique(s)

western blot: 2-4 μg/mL using HEK-293T cells expressing human LRRK2, and using rat and mouse brain extracts (S2 fraction)

UniProt 수납 번호

Q5S007

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... LRRK2(120892)
mouse ... Lrrk2(66725)
rat ... Lrrk2(300160)

Leucine-rich repeat protein kinase 2 (LRRK2) comprises multiple domains, including a leucine-rich repeat (LRR) domain, a Roc (Ras of complex proteins) GTPase domain followed by a C-terminal of ROC (COR) domain, a Ser/Thr kinase domain and a C-terminal Trp-Asp-40 (WD40) domain. The N-terminal region (?900 amino acids) contains ankyrin (ANK) repeats. The LRRK2 homologue LRRK1 shares domain structure similarity with LRRK2.