Merck Anti-WTX (N-terminal) antibody produced in rabbit

Anti-WTX (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~190 kDa

species reactivity

human

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

농도

~1.0 mg/mL

technique(s)

western blot: 1-2 μg/mL using HEK-293T cell lysates over expressing human WTX.

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... FAM123B(139285)

APC membrane recruitment protein 1 (AMER1) or Wilms Tumor on the X (WTX) gene, also known as FAM123B, comprises adenomatous polyposis coli (APC) interacting domains, nuclear localization signal (NLS), phospholipid binding region, six conserved block sequences and β-catenin binding region. The N-terminal region harbors the internal splicing sites (donor and acceptor). It encodes three isoforms AMER1, AMER2 and AMER3 APC, by alternative splicing at the N-terminus. WTX gene is localized on the X chromosome. The phosphatidylinositol (4,5)-bisphosphate binding site of the WTX aids its localization to the plasma membrane.