Merck Anti-FAM134B (lumenal) antibody produced in rabbit

Anti-FAM134B (lumenal) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

항체 형태

affinity isolated antibody

Quality Level

200

form

liquid

species reactivity

human

향상된 검증

recombinant expression
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농도

~1 mg/mL

UniProt 수납 번호

Q9H6L5

배송 상태

dry ice

저장 온도

−20°C

Five endoplasmic reticulum (ER)-resident proteins have been shown to function as receptors for selective ER-phagy: FAM134B, SEC62, RTN3, CCPG1 and ATL3.1-2 These integral membrane proteins appear to partition into different sub-domains of the ER. All of them harbor a sequential peptide motif within the cytoplasmic region, enabling binding to LC3/GABARAP proteins associated with phagophore membrane.1 FAM134B (also known as RETREG1 or JK-1) is the first ER-phagy receptor to be identified.2