Merck Anti-Cyclophilin B antibody, Mouse monoclonal

Anti-Cyclophilin B antibody, Mouse monoclonal

clone CYPB-3, purified from hybridoma cell culture

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

CYPB-3, monoclonal

form

buffered aqueous solution

분자량

antigen ~20 kDa

species reactivity

mouse, human, rat

향상된 검증

independent
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농도

~1.0 mg/mL

technique(s)

western blot: 2.5-5.0 μg/mL using whole cell extracts of human HepG2 or rat NRK cells.

동형

IgG1

UniProt 수납 번호

P23284

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... PPIB(5479)
mouse ... Ppib(19035)
rat ... Ppib(64367)

Monoclonal Anti-Cyclophilin B (mouse IgG1 isotype) is derived from the hybridoma CYPB-3 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to the C-terminal region of human Cyclophilin B, conjugated to keyhole limpet hemocyanin (KLH). Cyclophilin B (CypB) is a 21 kDa protein encoded by the peptidylprolyl isomerase B (PPIB) gene that belongs to the cyclophilin family, is a highly conserved class of proteins originally identified as cellular binding proteins for the immunosuppressive drug cyclosporin A. CypB is mainly located within the endoplasmic reticulum (ER) of all cell types.