Merck Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit

Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit

제품 개요

Affinity isolated antibody, buffered aqueous solution 형태의 항체로 인간 BACE-1 단백질 검출에 사용됩니다. Recombinant expression을 통한 향상된 검증(Enhanced Validation)을 제공합니다.

생물학적 소스

rabbit

품질 등급

200 (M-Clarity Program)

결합 형태

Unconjugated

항체 형태

Affinity isolated antibody

항체 유형

Primary antibodies

클론

Polyclonal

형태

Buffered aqueous solution

분자량

Antigen: 60–75 kDa

반응 종

Human

향상된 검증

Recombinant expression
Learn more about Antibody Enhanced Validation (Merck Technical Reference)

적용 기술

Western blot: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1

UniProt 수납 번호

P56817

배송 상태

Dry ice

저장 온도

−20°C

유전자 정보

Human BACE1 (23621)

제품 설명

The membrane-associated aspartic protease BACE-1 (β-site APP cleaving enzyme, Asp2 or memapsin 2) has been identified as β-secretase.
BACE-1 constitutes the predominant β-secretase activity in human brain tissue. It is highly expressed in neurons, the major site of Aβ generation.
BACE-1 is localized within the Golgi and endosomal compartments, among the several intracellular sites where Aβ is thought to be produced.
BACE-1 is initially an inactive proenzyme and localized in endoplasmic reticulum.

제품 스펙 요약

제품 이미지

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