Merck Anti-PKM2 (isoform M1) antibody produced in rabbit

Anti-PKM2 (isoform M1) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~60 kDa

species reactivity

human, rat, mouse

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

농도

~1.5 mg/mL

technique(s)

immunocytochemistry: 5-10 μg/mL using HeLa cells
immunohistochemistry: 20-30 μg/mL using formalin-fixed paraffin embedded human colon
immunoprecipitation (IP): 2-4 μg using rat brain extract (S2 fraction)
western blot: 1-2 μg/mL using mouse brain extract (S2 fraction)

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... PKM2(5315)

Pyruvate Kinase (PK) is a key regulatory enzyme in glycolysis and has four known isoforms, namely, L, R, M1 and M2. The M2 isoform has been linked to cancer metastasis. PK isoform M1 is expressed during the development of the embryo and is the dominant isoform in cardiac, brain and skeletal muscle tissues.