Merck Anti-Guanylyl Cyclase α1 antibody produced in rabbit

Anti-Guanylyl Cyclase α1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

IgG fraction of antiserum

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

~80 kDa

species reactivity

bovine, mouse, human, rat

포장

antibody small pack of 25 μL

향상된 검증

independent
Learn more about Antibody Enhanced Validation

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using trypsin-treated human, bovine and mouse heart tissue
immunoprecipitation (IP): 5-10 μg using 60-120 μg of a cytosolic fraction of rat brain
western blot: 1:10,000 using cytosolic fraction of rat brain

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... GUCY1A3(2982)
mouse ... Gucy1a3(60596)
rat ... Gucy1a3(497757)

The enzyme consists of α and β subunits of ~80kDa and ~70kDa respectively. Both the units are required for catalytic activity. The N-terminal domains of the subunits are essential for the stimulation of the enzyme by NO. Dimerization is mediated by the central portion of GC. The C-terminus domain of both subunits forms the catalytic domain.