Merck Anti-phospho-YAP1 (pTyr357) antibody produced in rabbit

Anti-phospho-YAP1 (pTyr357) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~65 kDa

species reactivity

human

포장

antibody small pack of 25 μL

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

농도

~1.5 mg/mL

technique(s)

indirect immunofluorescence: 5-10 μg/mL using HEK-293 cells co-transfected with human YAP1 and c-Abl
western blot: 0.5-1 μg/mL using HEK-293T cells co-transfected with human YAP1 and human c-Abl

UniProt 수납 번호

P46937

배송 상태

dry ice

저장 온도

−20°C

Gene Information

chicken ... YAP1(396171)
human ... YAP1(10413)
mouse ... Yap1(22601)

Yes-associated protein 1 (YAP1) is a 65 kDa and a modular adapter protein with multiple protein interaction domains that was originally identified based on its interaction with Src-family tyrosine kinase c-Yes. In addition to a SH3-binding motif, YAP1 contains a proline-rich amino terminus, a WW domain, a coiled-coil and a PDZ-binding motif at the extreme C-terminus. YAP1 binds to p73 through its WW domain and the PPPY motif of p73. This interaction is required for the ability of YAP1 to co-activate p73-responsive genes.