Merck Monoclonal Anti-Neurofilament 200 antibody produced in mouse

Monoclonal Anti-Neurofilament 200 antibody produced in mouse

Clone

NE14, ascites fluid

Quality Level

200

Biological Source

mouse

Conjugation

unconjugated

Antibody Form

ascites fluid

Antibody Type

primary antibody

Clone Information

NE14, monoclonal

Molecular Weight

Antigen apparent molecular weight: 200 kDa

Preservative

15 mM sodium azide

Species Reactivity

chicken, human, bovine, guinea pig, rabbit, pig, rat, mouse

Enhanced Validation

Independent (Antibodies)
Learn more about Antibody Enhanced Validation.

Applications / Techniques

• Immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:40
• Immunohistochemistry (frozen sections): suitable
• Microarray: suitable
• Western blot: suitable

Isotype

IgG1

UniProt Accession

P12036

Shipping Conditions

dry ice

Storage Temperature

−20°C

Gene Information

Human: NEFH (4744)

Description

Monoclonal Anti-Neurofilament 200 (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Neurofilaments are one of the five major groups of intermediate filaments (IFs) found predominantly in neuronal cells or tissues. They consist of three major proteins with apparent molecular weights of 68 kDa, 160 kDa, and 200 kDa, named NEFL (light), NEFM (medium), and NEFH (heavy), respectively. These proteins are synthesized in neuronal perikarya, assembled into filaments, and slowly transported within axons toward synaptic terminals.

Specifications

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