Merck Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

IgG fraction of antiserum

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen 95-100 kDa

species reactivity

human, mouse, rat

포장

antibody small pack of 25 μL

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000 using formic acid-treated sections of human Alzheimer′s disease (AD) brain
microarray: suitable
western blot: 1:4,000 using rat brain extract

UniProt 수납 번호

P05067

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... APP(351)
mouse ... App(11820)
rat ... App(54226)

Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APP is expressed in the brain. It is located on human chromosome 21. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells. Accumulation of the cleavage products of APP, such as the β-amyloid peptide, can cause Alzheimer′s disease.