Merck 7-Deaza-2′-deoxy-guanosine-5′-triphosphate

7-Deaza-2′-deoxy-guanosine-5′-triphosphate

95% (7-Deaza-dGTP, HPLC), ≤4% (7-Deaza-dGDP, HPLC), solution, 10 mM

7-Deaza-dGTP, −N7-dGTP, 7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt

Quality Level

100

assay

≤4% (7-Deaza-dGDP, HPLC)
95% (7-Deaza-dGTP, HPLC)

form

solution

포장

pkg of 200 μL (10 mM, 2 μmol)

manufacturer/tradename

Roche

농도

10 mM

배송 상태

dry ice

저장 온도

−20°C

SMILES string

NC1=NC(=O)c2ccn(C3CC(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)c2N1

InChI

1S/C11H17N4O13P3/c12-11-13-9-5(10(17)14-11)1-2-15(9)8-3-6(16)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1-2,6-8,16H,3-4H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,12,13,14,17)

InChI key

DLLXAZJTLIUPAI-UHFFFAOYSA-N

7-deaza-2′-deoxy-guanosine-5′-triphosphate is a nucleotide analog that is a candidate substrate for processive telomerase. The use of this analog improves PCR (polymerase chain reaction) yields. This compound also makes sequencing of GC rich sequences easier, especially if template amount is low and/or DNA quality is not good.