Merck Phytohemagglutinin-L (PHA-L)

Phytohemagglutinin-L (PHA-L)

from Phaseolus vulgaris

PHA-L

Quality Level

100

무균

non-sterile; 0.2 μm filtered

assay

>95% (SDS-PAGE)

form

lyophilized (clear, colorless solution after reconstitution)

포장

pkg of 5 mg

manufacturer/tradename

Roche

application(s)

hematology

배송 상태

wet ice

저장 온도

2-8°C

PHA-L is purified from Phaseolus vulgaris (red kidney bean) by standard chromatographic techniques.
Phytohemagglutinin (PHA), the lectin extract from the red kidney bean, consists of only L-type subunits (isolectin L4, leuko-agglutinin). It is an N-acetylgalactosamine/galactose sugar-specific lectin. PHA consists of five isolectins (L4E0, L3E1, L2E2, L1E3, L0E4) each being a tetramer held together by noncovalent forces. The subunits L (leukocyte reactive) have a high affinity for lymphocyte surface receptors, but little for those of erythrocytes, and are responsible for the mitogenic properties of the isolectins. E (erythrocyte reactive) is responsible for the erythrocyte-agglutinating properties.