Merck DNase I

DNase I

grade II, from bovine pancreas

Deoxyribonucleate 5′-oligonucleotido-hydrolase, Deoxyribonuclease

Quality Level

100

생물학적 소스

bovine pancreas

form

lyophilized

포장

pkg of 100 mg

manufacturer/tradename

Roche

technique(s)

DNA extraction: suitable

최적 pH

~7.0

배송 상태

wet ice

저장 온도

2-8°C

Bovine pancreatic deoxyribonuclease I (DNase I) is a DNA minor grove-interacting nuclease which shows relatively low specificity. This protein is composed of two central β sheets, each composed of six β-strands. This structure is surrounded by extensive loop and α-helical regions. This enzyme shares structural similarity to exonuclease III. DNase I is one of the most well characterized endonucleases of mammalian origin. It is a double-strand-specific endonuclease that requires bivalent cations for maximal activity.