Merck BMP-13 human

BMP-13 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

GDF-6, bone morphogenetic protein 13, Cartilage-Derived Morphogenetic Protein-2, CDMP-2

생물학적 소스

human

재조합

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized

효능

0.5-4 μg/mL ED50 (determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells.)

분자량

~27 kDa

포장

pkg of 50 μg

저장 조건

avoid repeated freeze/thaw cycles

불순물

endotoxin, tested

NCBI 수납 번호

Q6KF10

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... GDF6(392255)

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.