Merck WISP-1 human

WISP-1 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

WNT-1 inducible signaling pathway protein-1, CCN4, Wnt-1-induced secreted protein

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

효능

1.0-3.0 μg/mL ED50

분자량

38.1 kDa

포장

pkg of 20 μg

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

white

UniProt 수납 번호

O95388

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... WISP1(8840)

WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. WISP-1 is a beta catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 345 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.