Merck WISP-3 human

WISP-3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

CCN6, WNT-1 inducible signaling pathway protein-3

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

효능

0.2-0.3 μg/mL ED50

분자량

36.8 kDa

포장

pkg of 20 μg

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

white

UniProt 수납 번호

O95389

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... WISP3(8838)

WISP-3 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is predominantly expressed in the adult kidney, testis and fetal kidney and weaker expression in placenta, ovary, prostate, small intestine, and skeletally-derived cells. WISP-3 is required for normal postnatal skeletal growth and cartilage homeostasis. Human WISP-3 is a 36.8 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.