Merck Oncostatin M (209 aa) human

Oncostatin M (209 aa) human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

OSM

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

효능

≤2.0 ng/mL ED50

분자량

23.9 kDa

포장

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

white to off-white

UniProt 수납 번호

P13725

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... OSM(5008)

Oncostatin M (OSM) is produced by activated T cells, monocytes and Kaposi′s sarcoma cells. OSM shares several structural and functional characteristics with leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and ciliary neurotrophic factor (CNTF). The human OSM gene encodes for a 252 amino acid polypeptide, containing 25 amino acid signal sequence for secretion and a 227 precursor protein. Proteolytic processing of this precursor removes an 18 amino acid C-terminal peptide and generates the mature OSM form. Human OSM is active on murine cells. Recombinant human Oncostatin M is a 23.9kDa protein, containing 209 amino acid residues.