Merck Interleukin-6 human

Interleukin-6 human

IL-6, recombinant, expressed in E. coli, Carrier Free

IL-6, monocyte derived human B cell growth factor, interferon b2 (IFNb2), Interleukin-6 human, B cell stimulating factor (BSF-2), hepatocyte stimulating factor (HSF), plasmacytoma growth factor (PCT-GF), IL6, interleukin hybridoma/plasmacytoma-1 (IL-HP1)

Quality Level

200

생물학적 소스

human

재조합

expressed in E. coli

assay

>97% (SDS-PAGE)

form

lyophilized powder

효능

0.2-2.0 ng/mL Biological Activity EC50

품질

Carrier Free

분자량

26 kDa

포장

pkg of 10 μg

저장 조건

avoid repeated freeze/thaw cycles

불순물

≤1 EU/μg protein Endotoxin Level

색상

white

UniProt 수납 번호

P05231

저장 온도

−20°C

Gene Information

human ... IL6(3569)

Interleukin-6 (IL-6) is a multi-functional 26 kDa protein originally discovered in the medium of RNA-stimulated fibroblastoid cells1. IL-6 appears to be directly
involved in the immune responses that occur after infection and cellular injury, and it may prove to be as important as IL-1 and TNF-a in regulating the acute phase response2,3.

IL-6 is reportedly produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells, and hepatocytes. IL-6 induces multiple effects as indicated by its numerous synonyms4. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes5. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors6.This product is lyophilized from a 0.2 mm-filtered solution of phosphate buffered saline, pH 7.4, containing a stabilizer.

The product was prepared from raw materials verified to be carrier free.