Merck BAFF human

BAFF human

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

TALL-1, TNFSF13B, THANK, TNFSF20

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

분자량

17.0 kDa

포장

pkg of 20 μg

불순물

endotoxin, tested

UniProt 수납 번호

Q9Y275

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... TNFSF13B(10673)

BAFF, a member of the TNF superfamily of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.