Merck Amphiregulin human

Amphiregulin human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

AREG, Colorectum cell-derived growth factor (CRDGF), AR

생물학적 소스

human

재조합

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized powder

분자량

11.3 kDa

포장

pkg of 10 μg
pkg of 50 μg

UniProt 수납 번호

P15514

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... AREG(374)

Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, amphiregulin′s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.