Merck IL-24 human

IL-24 human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

MDA-7

생물학적 소스

human

재조합

expressed in CHO cells

assay

≥95% (HPLC)
≥95% (SDS-PAGE)

form

lyophilized

분자량

18.9 kDa

포장

pkg of 20 μg

불순물

<0.1 EU/μg endotoxin, tested

색상

white to off-white

UniProt 수납 번호

Q13007

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... IL24(11009)

IL-24 is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation.