Merck IL 17 A/F from mouse

IL 17 A/F from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

IL-17F, Interleukin 17A, IL-17A, Interleukin 17F, Interleukin 17 A/F

생물학적 소스

mouse

재조합

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized

분자량

30.7 kDa

포장

pkg of 1 mg
pkg of 10 μg
pkg of 50 μg

불순물

≤1 EU/μg endotoxin (LAL test)

UniProt 수납 번호

Q62386/Q7TN17

배송 상태

wet ice

저장 온도

−20°C

Gene Information

mouse ... IL17 A/F(16171)

Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17R receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant mouse IL-17AF is a non-glycosylated, disulfide-linked heterodimer. It is comprised of one monomeric subunit each of IL-17A and IL-17F, having a total of 271 amino acids and a molecular weight of 30.7 kDa.