Merck Interleukin-12 Protein, Recombinant human

Interleukin-12 Protein, Recombinant human

The recombinant human Interleukin-12 protein (or IL-12 protein) is a potent regulator of cell mediated immune responses & it induces IFN-gamma production by NK & T cells.

IL-12

Quality Level

100

생물학적 소스

human

재조합

expressed in CHO cells

assay

>98% (SDS-PAGE and HPLC)

specific activity

≥1.0 x 10E6 U/mg

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 ng/μg endotoxin (of IL-12; 1EU/μg)

input

sample type hematopoietic stem cell(s)

UniProt 수납 번호

P29459
P29460

배송 상태

dry ice

Interleukin-12 (IL-12) is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes, and connective tissue type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells. Human IL-12 is a disulfide linked heterodimeric protein with a molecular weight of 75 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits.