Merck EGF Protein, Human Recombinant Animal Free

EGF Protein, Human Recombinant Animal Free

This Recombinant animal free human EGF is manufactured using all non-animal reagents.

Epidermal Growth Factor, Urogastrone

Quality Level

100

재조합

expressed in E. coli

assay

>98% (SDS-PAGE and HPLC)

불순물

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI 수납 번호

NM_001963.2

UniProt 수납 번호

P01133

배송 상태

dry ice

Epidermal growth factor (EGF) is the founding member of the EGF family that also includes TGFα, amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), heparinbinding EGF like growth factor (HB-EGF), epigen, and the neuregulins (NRG)1-6. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.2 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds.