Merck BDNF Protein, Human Recombinant Animal Free

BDNF Protein, Human Recombinant Animal Free

The BDNF protein is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation & survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system.

Brain derived neurotrophic factor, Abrineurin

Quality Level

100

assay

>98% (SDS-PAGE and HPLC)

불순물

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI 수납 번호

NM_001709.3
NM_170731.3
NM_170732.3
NM_170733.2
NM_170734.2
NM_170735.4

UniProt 수납 번호

P23560

배송 상태

dry ice

Brain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions.