Merck Transforming Growth Factor-β1 from human platelets

Transforming Growth Factor-β1 from human platelets

TGF-β1, lyophilized powder, suitable for cell culture, 1 × 106 U/mg

TGF-β1

Quality Level

200

생물학적 소스

human

assay

≥97% (SDS-PAGE and N-terminal analysis)

form

lyophilized powder

효능

0.04-0.3 ng/mL ED50/EC50

품질

endotoxin tested

specific activity

1 × 106 U/mg

분자량

protein 25 kDa

포장

pkg of 1 μg
pkg of 10 μg

저장 조건

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

불순물

≤1 EU/μgtested (LAL test)

UniProt 수납 번호

P01137

저장 온도

−20°C

Gene Information

human ... TGFB1(7040)

The biologically active form of TGF-β1 (transforming growth factor-β1 human) exists as a disulphide-linked homodimer. In mammals, three isoforms of TGF-β has been identified : TGF-β1, TGF-β2 and TGF-β3. TGF-β1 encodes a 25 kDa peptide. TGF-β1 precursor polypeptide is characterized with hydrophobic signal sequence, pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The TGF-β1 gene is mapped to human chromosome 19q13.2.