Merck Interleukin-6 human

Interleukin-6 human

recombinant, expressed in HEK 293 cells, suitable for cell culture

IL-6

Quality Level

200

생물학적 소스

human

재조합

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE)

form

lyophilized powder

효능

0.2-2 ng/mL EC50

품질

endotoxin tested

분자량

calculated mol wt 20.8 kDa (183 amino acids glycosylated protein)

포장

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

불순물

≤0.1 EU/μg protein (LAL test)

색상

white

UniProt 수납 번호

P05231

저장 온도

−20°C

Gene Information

human ... IL6(3569)

Interleukin 6 (IL-6) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. IL-6 is a multifunctional cytokine with well-defined pro- and anti-inflammatory properties. IL-6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. The O-linked sugar chain of IL-6 is thought to contribute to the stability of the cytokine through polymerization suppression and/or conformational changes, exemplifying the significance of its expression in a human expression system (which allows proper glycosylation).