Merck Interleukin-6 from mouse

Interleukin-6 from mouse

IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free

IL-6, mIL-6

Quality Level

200

생물학적 소스

mouse

재조합

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

효능

0.02-0.2 ng/mL EC50

품질

endotoxin tested

분자량

~21.7 kDa

포장

pkg of 5 and 25 μg

technique(s)

cell culture | mammalian: suitable

불순물

≤1.0EU/mg

색상

white

UniProt 수납 번호

P08505

저장 온도

−20°C

Gene Information

mouse ... Il6(16193)

Interleukin-6 (IL-6) is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 and TNF-α in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 induces multiple effects, as indicated by its numerous synonyms: plasmacytoma growth factor (PCT-GF), interferon-β-2 (IFN-β2), monocyte derived human B cell growth factor, B cell stimulating factor (BSF-2), hepatocyte stimulating factor (HSF), Interleukin Hybridoma/Plasmacytoma-1 (IL-HP1). In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 also potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors.