Merck Beta NGF human
인간 유래 베타 신경성장인자(Beta NGF)는 E. coli에서 발현된 재조합 단백질로, 세포 배양에 적합합니다. ≥98% 순도(HPLC, SDS-PAGE)로 정제되었으며, <0.1 EU/μg 엔도톡신 수준을 보입니다. 감각 및 교감신경 발달과 B세포 생존에 중요한 역할을 합니다.
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Beta NGF human
제품 설명
Recombinant human β-Nerve Growth Factor (β-NGF), expressed in E. coli, with ≥98% purity (SDS-PAGE, HPLC). Suitable for cell culture applications.
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3, and NT-4. These proteins belong to the cysteine-knot family of growth factors that form stable dimeric structures. β-NGF acts through its receptor β-NGFR and is essential for the development and maintenance of sensory and sympathetic nervous systems. It also functions as a growth and differentiation factor for B lymphocytes, enhancing B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer of two 13.5 kDa monomers (240 amino acids total), with three disulfide bonds required for biological activity.
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