
Merck IL-4 human
Recombinant human IL-4, animal-component free, expressed in E. coli. ≥98% purity (SDS-PAGE, HPLC). Supports mammalian cell culture and immune cell differentiation studies. Lyophilized form, stored at −20°C.
- 카탈로그번호
- SRP3093-20UG
- 브랜드
- Merck Sigma
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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IL-4 human
제품 개요
Animal-component free recombinant human IL-4 expressed in E. coli, ≥98% purity (SDS-PAGE, HPLC), suitable for cell culture.
Also known as BCGF, BCDF, or B cell stimulating factor (BSF-1).
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses, including proliferation, survival, and gene expression. Produced by mast cells, T cells, and bone marrow stromal cells, IL-4 promotes differentiation of naive CD4+ T cells into Th2 cells, which secrete IL-4, IL-5, IL-6, IL-10, and IL-13 to support humoral immune responses.
It also regulates immunoglobulin class switching to IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells is associated with elevated IgE and allergic responses.
Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
제품 사양
| 항목 | 내용 |
|---|---|
| 생물학적 소스 | Human |
| 재조합 발현 | E. coli |
| Assay | ≥98% (HPLC), ≥98% (SDS-PAGE) |
| 형태 | Lyophilized |
| 효능 (ED50) | ≤0.2 ng/mL |
| 분자량 | 14.9 kDa |
| 포장 단위 | 20 μg |
| 적용 기술 | Cell culture (mammalian: suitable) |
| 불순물 | <0.1 EU/μg endotoxin, tested |
| 색상 | Off-white to yellow |
| UniProt 번호 | P05112 |
| 배송 상태 | Wet ice |
| 저장 온도 | −20°C |
| Gene Information | human IL4(3565) |
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