Merck PDGF-BB from mouse
Recombinant mouse PDGF-BB, expressed in E. coli, ≥98% purity (HPLC/SDS-PAGE). Suitable for mammalian cell culture. Promotes cell proliferation and differentiation. Supplied lyophilized, stored at −20°C.
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- SRP3229-10UG
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- Merck Sigma
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- Protein
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PDGF-BB from Mouse
제품 설명
Recombinant mouse PDGF-BB, expressed in E. coli, with ≥98% purity confirmed by SDS-PAGE and HPLC.
Also known as Osteosarcoma-derived Growth Factor (ODGF) or Glioma-derived Growth Factor (GDGF).
Suitable for use in cell culture applications.
제품 사양
| 항목 | 내용 |
|---|---|
| 생물학적 소스 | Mouse |
| 재조합 발현 | E. coli |
| Assay | ≥98% (HPLC), ≥98% (SDS-PAGE) |
| 형태 | Lyophilized |
| 효능 (ED50) | 1.0–2.0 ng/mL |
| 분자량 | 24.4 kDa |
| 포장 단위 | 10 μg |
| 적용 기술 | Cell culture (mammalian: suitable) |
| 불순물 | <0.1 EU/μg endotoxin, tested |
| 색상 | Off-white to yellow |
| UniProt 번호 | P31240 |
| 배송 상태 | Wet ice |
| 저장 온도 | −20°C |
| Gene Information | Mouse PDGFB(18591) |
추가 정보
PDGFs (platelet-derived growth factors) are disulfide-linked dimers consisting of two 12.0–13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B.
Two distinct signaling receptors, PDGFR-α and PDGFR-β, mediate their activity.
PDGFR-α binds all three PDGF forms with high affinity, while PDGFR-β interacts specifically with PDGF-BB and PDGF-AB.
Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer composed of two B chains (218 total amino acids).
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