Merck PDGF-BB from mouse
Recombinant mouse PDGF-BB, expressed in E. coli, ≥98% purity (HPLC/SDS-PAGE). Suitable for mammalian cell culture. Promotes cell proliferation and differentiation. Supplied lyophilized, stored at −20°C.
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PDGF-BB from Mouse
제품 설명
Recombinant mouse PDGF-BB, expressed in E. coli, with ≥98% purity confirmed by SDS-PAGE and HPLC.
Also known as Osteosarcoma-derived Growth Factor (ODGF) or Glioma-derived Growth Factor (GDGF).
Suitable for use in cell culture applications.
추가 정보
PDGFs (platelet-derived growth factors) are disulfide-linked dimers consisting of two 12.0–13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B.
Two distinct signaling receptors, PDGFR-α and PDGFR-β, mediate their activity.
PDGFR-α binds all three PDGF forms with high affinity, while PDGFR-β interacts specifically with PDGF-BB and PDGF-AB.
Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer composed of two B chains (218 total amino acids).
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