Merck Heregulin beta -1 human

Heregulin beta -1 human

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Neuregulin1, NRG1-b1

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

효능

≤0.5 ng/mL

분자량

7.5 kDa

포장

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

white to off-white

UniProt 수납 번호

Q02297

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... NRG1(3084)

Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). HRG1-β1 (heregulin-β1, also referred to as NRG1-β1) contains an Ig (immunoglobulin) domain and an EGF (epidermal growth factor)-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. The gene HRG1-β1 is mapped to human chromosome 8p12. Recombinant human Heregulin-β1 is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulin-β1 (65 amino acid residues).