Merck Interleukin-6 human

Interleukin-6 human

IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

hIL-6, IL-6

Quality Level

300

생물학적 소스

human

재조합

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

효능

0.2-2.0 ng/mL ED50/EC50

품질

endotoxin tested

분자량

26 kDa

포장

pkg of 10 and 50 μg

저장 조건

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

불순물

≤1.000 EU/μg

색상

white

UniProt 수납 번호

P05231

저장 온도

−20°C

Gene Information

human ... IL6(3569)

Interleukin-6 (IL-6) is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 and TNF-α in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 induces multiple effects, as indicated by its numerous synonyms: plasmacytoma growth factor (PCT-GF), interferon-β-2 (IFN-β2), monocyte derived human B cell growth factor, B cell stimulating factor (BSF-2), hepatocyte stimulating factor (HSF), Interleukin Hybridoma/Plasmacytoma-1 (IL-HP1). In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 also potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors.