Merck Epidermal Growth Factor, human (hEGF)
재조합 인간 EGF(hEGF)로, 세포 배양 및 성장 인자 연구에 적합. E. coli에서 발현되어 고순도(>95% HPLC)로 정제된 동결건조 형태. 세포 증식 및 분화 촉진에 활용 가능하며 −20°C에서 보관.
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Epidermal Growth Factor, human (hEGF)
Recombinant (E. coli)
Recombinant Epidermal Growth Factor, human (hEGF), is produced in E. coli and purified by standard chromatographic techniques. It is supplied as a 100 μg white lyophilizate, filtered through a 0.2 μm membrane.
Epidermal Growth Factor (EGF) is a small mitogenic polypeptide found in many mammalian species and distributed throughout various tissues and body fluids.
Human EGF is identical to β-urogastrone, known for its ability to inhibit gastric acid secretion. Of the 53 amino acids in human EGF, 37 are identical to those in mouse EGF (70% homology), and both share the same disulfide bond pattern.
EGF stimulates proliferation and differentiation of a wide variety of ectodermal and mesodermal cells, such as fibroblasts, glial cells, keratinocytes, epithelial cells, endothelial cells, and chondrocytes.
It is a common component in serum-free media formulations for various cell types.
제품 사양
| 항목 | 내용 |
|---|---|
| 품질 등급 | 100 |
| 생물학적 소스 | Human |
| 재조합 발현 | E. coli |
| 순도 (Assay) | >95% (HPLC) |
| 형태 | Lyophilized |
| 효능 (EC50) | <0.5 ng/mL |
| 분자량 | 6200 Da |
| 포장 단위 | 100 μg |
| 제조사/상표명 | Roche |
| 색상 | White |
| 저장 조건 | Avoid repeated freeze/thaw cycles |
| 기술 적용 | Cell culture (mammalian: suitable) |
| 배송 상태 | Dry ice |
| 저장 온도 | −20 °C |
| UniProt 번호 | Q6QBS2 |
| 유전자 정보 | EGF (1950) |
참고 정보
The EGF receptor is one of the best understood growth factor receptors. The oncogene v-erbB encodes a product homologous to a portion of the EGF receptor lacking the EGF-binding domain, potentially leading to constitutive activation without ligand binding.
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