Merck Interleukin-1β human

Interleukin-1β human

IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested

Lymphocyte activating factor, IL-1β

Quality Level

100

생물학적 소스

human

재조합

expressed in HEK 293 cells

assay

≥95% (SDS-PAGE)

form

lyophilized powder

효능

≤0.05 ng/mL EC50

품질

endotoxin tested

분자량

dimer 18-25 kDa (glycosylated)

포장

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

불순물

<1 EU/μg

UniProt 수납 번호

P01584

저장 온도

−20°C

Gene Information

human ... IL1B(3553)

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.