Merck MAPTRIX-C-TAIPSCPEGTVPLYS

MAPTRIX-C-TAIPSCPEGTVPLYS

Collagen Mimetic, aqueous solution

무균

Filtered sterilized solution

form

aqueous solution

분자량

~24.1 kDa

포장

pkg of 2.5 mg

농도

0.5 mg/mL protein

technique(s)

cell culture | mammalian: suitable

결합 특이성

Domain: α3(IV) NC1
Binding Motif: TAIPSCPEGTVPLYS

배송 상태

ambient

저장 온도

2-8°C

MAPTrix™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion. The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation. A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.