Merck Complement C5 deficient serum human

Complement C5 deficient serum human

for complement assays

Quality Level

200

생물학적 소스

human

form

solution

technique(s)

activity assay: suitable

UniProt 수납 번호

P01031

저장 온도

−70°C

Gene Information

human ... C5(727)

Complement C5 deficiencies in humans are rare, but often associated with recurrent infections by Neisseria spp. (such as meningitis). Deficiency in C5 results in an impairment of hemolytic activity from both the classical and alternative pathway of the complement system. Recently, genetic research has revealed that a 153 bp deletion in exon 30 results in complete C5 deficiency. Research has also implicated C5 deficiency in a predisposition to cardiac dysfunction when cardiac injury occurs.