Merck Insulin-Transferrin-Sodium Selenite Supplement

Insulin-Transferrin-Sodium Selenite Supplement

suitable for cell culture, lyophilized, pkg of 50 mg (for 5 l medium)

ITS

Quality Level

100

생물학적 소스

human serum (transferrin)
synthetic (sodium selenite)

재조합

expressed in human cells

무균

non-sterile; 0.2 μm filtered

assay

>98% (Transferrin, SDS-PAGE)
>99% (Insulin, HPLC)
>99% (Sodium selenite)

form

lyophilized

포장

pkg of 50 mg (for 5 l medium)

manufacturer/tradename

Roche

technique(s)

cell culture | mammalian: suitable

solubility

water: miscible

UniProt 수납 번호

P01317
P02786

배송 상태

wet ice

저장 온도

2-8°C

Gene Information

bovine ... INS(280829)
human ... TFRC(7037)

The insulin-transferrin-sodium selenite (ITS) supplement comprises three of the most crucial growth factors for many cell types. Insulin is a component of serum-free media formulations for all primary cells and cell lines. It stimulates cell growth, increases fatty acid and glycogen synthesis in a serum-free medium. Transferrin is an essential growth factor for many cell types. Selenium is very often necessary for optimal cell growth. ITS permits an appreciable reduction in serum requirements for cellular growth. ITS is also an antioxidant that supports the growth of in vivo derived (IVD) embryos. Insulin promotes embryonic growth and metabolism. The iron transport in the embryo is mediated by transferrin. Sodium selenite protects from oxidative damage and inhibits lipid peroxidation. ITS is useful in human chondrocytes monolayer culture.