Thermo Fisher Scientific Noto Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Noto

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644754

Product Specific Information

Immunogen sequence: CVHPAFWTAA SLCATGGLPW ACPTSWLPAY LSVGFYPVPG PRVAPVCGLL GFGVTGLELA HCSGLWAFPD WAPTEDLQDT ERQQKRVRTM FNLE

Highest antigen sequence identity to the following orthologs: Mouse - 44%, Rat - 41%.

Target Information

Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.