Thermo Fisher Scientific Noto Polyclonal Antibody
Rabbit polyclonal antibody recognizing human Noto recombinant protein. Suitable for research use in studying notochord development and transcription regulation. Supplied as liquid, 0.1 mg/mL concentration. Store at 4°C short term or -20°C long term.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Noto |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644754 |
Product Specific Information
Immunogen sequence:
CVHPAFWTAA SLCATGGLPW ACPTSWLPAY LSVGFYPVPG PRVAPVCGLL GFGVTGLELA HCSGLWAFPD WAPTEDLQDT ERQQKRVRTM FNLE
Antigen sequence identity:
- Mouse: 44%
- Rat: 41%
Target Information
Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process. Required for the expression of components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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