Thermo Fisher Scientific DISP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DISP2. Recombinant protein control fragment (Product #RP-98095). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DISP2,uniProtId:A7MBM2-1,ncbiNodeId:9606,antigenRange:209-317,antigenLength:1401,antigenImageFileName:PA5-63790_DISP2_A7MBM2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63790_DISP2_A7MBM2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640615

Product Specific Information

Immunogen sequence: DIGSKLVVWR ALQALTGPRK LLFLSPDLEL NSSSSHNTLR PAPRGSAQES AVRPRRMVEP LEDRRQENFF CGPPEKSYAK LVFMSTSSGS LWNLHAIHSM CRMEQDQIR

Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 66%.

Target Information

DISP2, also known as dispatched homolog 2, is a protein that plays a critical role in the regulation of the hedgehog signaling pathway. It is involved in the transport and release of hedgehog ligands, which are important for cellular differentiation and tissue development. Mutations in the DISP2 gene have been associated with various developmental disorders, including holoprosencephaly and cleft lip and palate. DISP2 is also being studied as a potential therapeutic target in cancer, as the hedgehog pathway is frequently dysregulated in various types of tumors

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.