
Thermo Fisher Scientific HSPB8 Recombinant Rabbit Monoclonal Antibody (23GB1980)
HSPB8 단백질을 인식하는 토끼 단클론 항체로, Western blot, ICC, Flow Cytometry에 적합합니다. 재조합 형식으로 높은 특이성과 재현성을 제공하며, HEK293F 시스템에서 발현되었습니다. 인간 및 생쥐 시료에 반응합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1980 |
| Immunogen | A synthesized peptide derived from human HSPB8/HSP22 (5–32AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by the HSPB8 gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal region. Its expression is induced by estrogen in estrogen receptor-positive breast cancer cells. HSPB8 functions as a chaperone in association with Bag3, a stimulator of macroautophagy, and is involved in the regulation of cell proliferation, apoptosis, and carcinogenesis. Mutations in this gene have been associated with various neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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