Thermo Fisher Scientific MAD4 Polyclonal Antibody
Thermo Fisher Scientific의 MAD4 Polyclonal Antibody는 인간 MXD4 단백질의 N-말단 펩타이드(aa 5-54)에 특이적으로 반응하는 항체입니다. Western blot 및 IHC(P) 검증 완료, 고순도 친화 크로마토그래피 정제, 0.5 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human MXD4 (aa 5–54) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607846 |
Product Specific Information
- Peptide sequence: SLLILLEAAE YLERRDREAE HGYASVLPFD GDFAREKTKA AGLVRKAPNN
- Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 93%
Human: 100%
Mouse: 86%
Rabbit: 93%
Sheep: 93%
Target Information
This gene belongs to the MAD gene family, which encodes basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein to form a transcriptional repression complex.
MAD proteins compete with MYC for MAX binding, where MYC-MAX complexes act as transcriptional activators.
Rodent studies suggest MAD genes function as tumor suppressors and regulate cell growth in differentiating tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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