Thermo Fisher Scientific GluR6 Recombinant Rabbit Monoclonal Antibody (ARC1718)
Recombinant rabbit monoclonal antibody targeting GluR6 (GRIK2). Validated for WB, IHC-P, and ELISA. High specificity and reproducibility. Suitable for neuroscience and receptor function studies. For research use only.
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Thermo Fisher Scientific GluR6 Recombinant Rabbit Monoclonal Antibody (ARC1718)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1718 |
| Immunogen | Synthetic peptide corresponding to amino acids 50–150 of human GRIK2 (Q13002) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.27 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898121 |
Product Specific Information
- Positive samples: Mouse brain, 293T cells
- Immunogen sequence:
MGAEELAFRF AVNTINRNRT LLPNTTLTYD TQKINLYDSF EASKKACDQL SLGVAAIFGP SHSSSANAVQ SICNALGVPH IQTRWKHQVS DNKDSFYVSL Y
Target Information
Glutamate receptors are the primary excitatory neurotransmitter receptors in the mammalian brain and play key roles in normal neurophysiological processes. The kainate family of glutamate receptors functions as ligand-activated ion channels, composed of four subunits including the product encoded by this gene. The subunit is edited at multiple sites within the first and second transmembrane domains, affecting receptor structure and function. Alternative splicing produces different isoforms. Mutations in GRIK2 are associated with autosomal recessive cognitive disability and neurodevelopmental disorders such as impaired language and ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-38204_GluR6_Q13002-1_Rabbit.svg, MA5-38204_GluR6_Q13002-1_Rabbit_PDP.jpeg)
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