Thermo Fisher Scientific CD28 Monoclonal Antibody (10F3), FITC
인간 CD28 항원을 인식하는 Mouse IgG1 단클론 항체로 FITC 형광 표지. Flow Cytometry에 사용 가능하며 높은 형광 효율과 수용성 제공. PBS/BSA 완충액에 보관하며 4°C 암소 저장.
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Thermo Fisher Scientific CD28 Monoclonal Antibody (10F3), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-Dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F3 |
| Immunogen | Human CD28 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536492 |
Additional Formats
- Unconjugated
- PE
- Request custom conjugation
Product Specific Information
FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily, constitutively expressed on most peripheral blood T lymphocytes. CD28 acts as a critical T cell costimulatory receptor providing a secondary activation signal via binding CD80 and CD86 on antigen-presenting cells. It prevents T cells from entering an anergic state or undergoing premature apoptotic death. In murine lymphoid organs and blood, all CD4+ and CD8+ T cells express CD28. Expression levels vary depending on cell maturity. CD28 dysfunction is associated with diseases such as mycosis fungoides and Sezary’s disease.
Reagent Type
Analyte Specific Reagent
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