Thermo Fisher Scientific CML Latex Beads, 4% w/v, 0.5 μm

Invitrogen™ CML Latex Beads, 4% w/v, 0.5 μm

Microspheres (also called latex beads or latex particles) are spherical particles in the colloidal size range formed from amorphous polymers such as polystyrene. The arrangement of polystyrene chains makes the surface highly hydrophobic, ideal for adsorption of materials such as proteins.

These carboxylate-modified (CML) latex particles are produced by copolymerizing carboxylic acid-containing polymers. The result is a latex particle with a highly charged, relatively hydrophilic, and somewhat “fluffy” surface layer. CML particles are electrosterically stabilized and remain stable in electrolyte concentrations up to 1M univalent salt. They are negatively charged with a polyelectrolyte surface character. At approximately pH 10, all carboxyl groups are ionized, yielding a hydrophilic latex.

Microspheres Are Available in Many Sizes and Surface Functionalities

• 25 sizes available: 0.02 μm to 16 μm
• 20 different surface types for conjugation to various materials
• Surfactant-free for ultraclean performance
• Available in quantities from milliliters to 500 liters

Key Applications

• Instrument calibration (flow cytometry, microscopy, HTS, HCS)
• Flow testing (microfluidics, blood flow, water flow, air flow)
• Cell biology tracers (cell differentiation, cell tracing)
• Immunoassays (agglutination tests, ELISA, particle capture, contrast reagents)

Additional Information

Read a technical overview of microspheres and learn more about high-activity, super-active, and specialty beads, as well as bead-coupling protocols on the IDC Surfactant-free Latex Beads page.

Custom Microsphere Services

If you do not find the microsphere you need in the stocked list, Thermo Fisher Scientific offers custom microsphere production and conjugation services. These services are efficient, confidential, and ISO 13485:2000 certified.

For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.

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