Thermo Fisher Scientific LPIN3 Monoclonal Antibody (OTI1F8), TrueMAB
LPIN3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 유래 LPIN3 전체 길이 재조합 단백질을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 연구용으로만 사용되며 안정적인 저장 및 운송 조건을 갖추고 있습니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F8 |
| Immunogen | Full length human recombinant protein of human LPIN3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Humans with lipodystrophy exhibit loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice with mutations in the fatty liver dystrophy gene show similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was identified as Lpin1, encoding a nuclear protein named lipin. Lpin1 mRNA is highly expressed in adipose tissue and induced during preadipocyte differentiation, indicating its role in normal adipose tissue development and as a candidate gene for human lipodystrophy.
Database searches revealed homologous sequences in mouse and human genomes: LPIN1, LPIN2, and LPIN3.
- Human LPIN1 maps to chromosome 2p25
- LPIN2 to 18p11
- LPIN3 to 20q11–q12
- Mouse Lpin1, Lpin2, and Lpin3 map to chromosomes 12, 17, and 2 respectively.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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