Thermo Fisher Scientific PP2A alpha Polyclonal Antibody
PP2A alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunohistochemistry에 적합. Human에 반응하며 bovine, porcine, rabbit에서도 예측 반응. 고순도 정제, 1.8 mg/mL 농도, 연구용으로만 사용.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–30 amino acids from the N-terminal region of human PP2A alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2169638 |
Product Specific Information
This antibody is predicted to react with bovine, porcine, and rabbit based on sequence homology.
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate diverse cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases are key players in this process. The protein phosphatase (PP) holoenzyme typically consists of a regulatory, a variable, and a catalytic subunit. Four major families of catalytic subunits are known: PP1, PP2A, PP2B (calcineurin), and PP2C. The PP2A family includes PP2A alpha and PP2A beta, while PPX (PP4) is a putative member of a novel PP family.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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