Thermo Fisher Scientific MRPL47 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRPL47 for IHC (paraffin) applications. Recombinant protein immunogen ensures specificity. High purity via antigen affinity chromatography. Provided in liquid form with PBS/glycerol buffer. Suitable for mitoch...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL47. Recombinant protein control fragment (Product #RP-96340). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644158 |
Product Specific Information
- Immunogen sequence:
LKERNMLLTL EQEAKRQRLP MPSPERLDKV VDSMDALDKV VQEREDALRL LQTGQERARP GAWRRDIFGR IIWHKFKQWV I - Highest antigen sequence identity:
- Mouse: 91%
- Rat: 93%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—reversed compared to prokaryotic ribosomes. Mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species in sequence and biochemical properties, complicating recognition by sequence homology.
This gene encodes a 39S subunit protein and is located adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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