Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI1F7), TrueMAB
DOK7 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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- TA504789
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- pk
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Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI1F7), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F7 |
| Immunogen | Full length human recombinant protein of DOK7 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The DOK7 protein is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase, required for postsynaptic differentiation and clustering of acetylcholine receptors in myotubes. It can induce autophosphorylation of muscle-specific receptor kinase. Mutations in DOK7 cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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